Translation of "adrenocortical" to English language:
Examples (External sources, not reviewed)
| Estes incluiram toxicidade adrenocortical dose dependente (acumulação do pigmento lipofuscina e ou perda celular no parênquima) em ratos após 104 semanas com 20 a 60 mg kg dia (3 a 10 vezes a AUC do estado de equilíbrio média na dose humana máxima recomendada) e aumento dos carcinomas adrenocorticais e adenomas carcinomas adrenocorticais combinados no rato fêmea com 60 mg kg dia (10 vezes a AUC do estado de equilíbrio média na dose humana máxima recomendada). | These included dose dependent adrenocortical toxicity (lipofuscin pigment accumulation and or parenchymal cell loss) in rats after 104 weeks at 20 to 60 mg kg day (3 to 10 times the mean steady state AUC at the maximum recommended human dose) and increased adrenocortical carcinomas and combined adrenocortical adenomas carcinomas in female rats at 60 mg kg day (10 times the mean steady state AUC at the maximum recommended human dose). |
