The high price of such drugs is limiting their impact as well.

Incompetence during a political transition has a high price.

But this has a huge, huge impact on the environment.

It has an amount of impact on the planet that's measurable.

Chagas disease has a serious economic impact on the United States and the world.

The city has a Gini coefficient of 0.48, indicating a high level of inequality.

Although the HST has clearly helped astronomical research, its financial cost has been large.

It's a project that has the potential to make a huge impact around the world.

There's no escaping the fact that everything we eat has a global impact.

Impact Effect on agriculture Precipitation, especially rain, has a dramatic effect on agriculture.

The impact of the ongoing reappraisal of risk in financial markets on the real economy is still surrounded by unusually high uncertainty .

Lebanon has a very high level of public debt and large external financing needs.

When X has a larger standard deviation, σ 1, the distribution of Y is strongly skewed.

They are found along the coastlines of the Indian Ocean and Indonesia.

The operational framework has also shown a high degree of flexibility in adapting to changing financial environments .

But big corporations often use those small companies to make use of genetic resources, Adriana says.

The Austrian schilling has demonstrated a high degree of exchange rate stability sustained for a long period vis a vis the Deutsche Mark .

It has impressive universities and a high education level, well managed global companies, and a strong work ethic.

It would make a very uplifting world.

And it's going to have an impact.

It is a very big impact.

market depth , in the meaning that they are traded on a market which is able to absorb a large volume of transactions , with such trading of large amounts having a limited impact on their price

Espinoza, E.O., and M. J.

In the European Union the sulfur content has dramatically reduced during the last 20 years.

The impact of the ICTY worldwide has been multifaceted.

Again, its effect, thus far, has been significant.

All of quality control, which has had a major impact on industrial processing, is underpinned by statistics.

The SEPA project will have a major impact on all stakeholders , creating opportunities as well as challenges .

Minimum safety and efficiency standards and recommendations are therefore warranted to guide stakeholders in payment 11

This too has an impact on the ability of a participant to deliver securities when needed .

More boring, but you still have that kind of colliding and bumping.

For wind, there's a larger area, but much smaller footprint.

a high level of access to justice

Impact on climate The Himalayas have a profound effect on the climate of the Indian subcontinent and the Tibetan Plateau.

However, after a skill reaches a certain level, books no longer have an impact.

This is a substantially large impact.

That's going to have amazing impacts.

It had an immediate impact.

They all happen over a period of time equal to 10 to the 10 to the 120 years.

When Wal Mart declares it's going to go green and be profitable, it has a powerful impact on other great institutions.

And the impact of the learning landscape has been pretty surprising and amazing.

There's also a huge emotional impact.

There's an impact, it's cumulative.

It had a huge impact on life.

Calvinism had a very strong impact.