That is a huge effect.

Technological change had an enormous effect on strategy, but little effect on leadership.

This had an immense effect on Native language acquisition.

And when Freud discovered his sense of the unconscious, it had a vast effect on the climate of the times.

To be sure, pharmacogenetics has made a profound difference for some patients.

Pistole, M., Roberts, A., Mosko, J. E. (2010).

That's an enormous amount of cars.

Portion size is obviously a massive, massive problem.

That's an enormous benefit.

So, a huge problem.

That's a big skull.

Labeling is a massive problem.

So it was a massive effort.

This takes an enormous toll.

He has a huge cock.

We made a huge mistake.

I have a huge sailboat.

That's a huge challenge.

This is a huge challenge for us to do that.

There's also a huge emotional impact.

Hugely viral video. Extremely popular.

A huge scandal for a few weeks.

And that's going to pose an enormous problem.

This is a major professional mistake.

China is a huge country.

Brazil is a huge country.

Brazil is a very big country.

It proved a colossal success.

GT Thank you. It's been a great pleasure.

So this is a huge practical problem.

But it's also a huge social problem.

This book became, naturally, an enormous best seller.

Yesterday we went into a huge maze.

His program had enormous success.

He has a broad understanding of the world.

Could I ask you a big favor?

We have a big oak tree in our backyard.

So this is really the enormous challenge that we have.

And what does the big black hole do?

We also see a big DIY movement.

There's a great big elephant in the room called the economy.

So this is a huge social win, too.

This structural shift has enormous practical significance.

There is a large garden at the back of his house.

The street was blocked by a huge truck.